Thuy was born in Ho Chi Minh City in 1962. After graduating from the Conservatoire de Musique as a violinist, she embarked on her painting career in 1991. Her work has since been included in many Exhibits in Asia, Europe and North America. She is a member of the Fine Arts Association of Ho Chi Minh City, Vietnam.

Her subject matters include women in traditional dress, semi abstract compositions of rice bowls, still life, houses, and waterside scenes.